breast cancer
Conditions
Interventions
indocyanine green group:Indocyanine green was developed and traced under fluorescence cavity microscope.
blue dye group:The tracer was developed by methylene blue under fluorescence cavity.
indocyanine green combined with blue dye group:Indocyanine green and methylene blue were developed under fluorescence cavity.
Sponsors
Zhujiang Hospital of Southern Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1. Patients with preoperative clinical staging of cT1-T3, N0, M0. 2. Clinical examination of axillary lymph nodes was negative. 3. Aged >= 18 years.
Exclusion criteria
Exclusion criteria: 1. Distant metastasis of cancer. 2. With inflammatory breast cancer. 3. Suspicious axillary lymph node metastasis was found by clinical or imaging examination. 4. Previous history of axillary surgery and trauma. 5. Allergic to iodine or indocyanine green. 6. Received preoperative drug therapy (including endocrine therapy and neoadjuvant chemotherapy). 7. Incomplete records of medical records. 8. Pregnant or lactating patients. 9. Patients suffering from serious underlying diseases such as heart, brain, kidney and/or mental illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sentinel lymph node identification rate;The median number of metastatic sentinel lymph nodes identified by indocyanine green combined with blue dye, indocyanine green, and blue dye, respectively; | — |
Secondary
| Measure | Time frame |
|---|---|
| Metastatic sentinel lymph node identification rate;Sentinel lymph node visualization rate;Metastatic sentinel lymph node visualization rate;The median number of sentinel lymph nodes identified by indocyanine green combined with blue dye, indocyanine green, and blue dye, respectively;Operation time of sentinel lymph node biopsy;Postoperative incision infection rate; | — |
Countries
China
Contacts
Public ContactZhang Pusheng
Zhujiang Hospital of Southern Medical University
Outcome results
None listed