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Association between the polymorphism of PLA2R gene and idiopathic membranous nephropathy in Heilongjiang

Association between the polymorphism of PLA2R gene and idiopathic membranous nephropathy in Heilongjiang

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200065763
Enrollment
Unknown
Registered
2022-11-14
Start date
2022-12-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

idiopathic membranous nephropathy

Interventions

IMN group:none
Healthy control group:none

Sponsors

Heilongjiang Academy of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. The diagnosis of IMN is confirmed in patients with positive renal biopsy puncture or PLA2R test; 2. Pathological diagnosis consistent with the diagnostic criteria for Ehrenreich-Churg membranous nephropathy.

Exclusion criteria

Exclusion criteria: 1.IMN group: (1) Patients with secondary membranous nephropathy; (2) Patients with other kidney diseases; (3) Patients treated with hormones or immunosuppressants; (4) Complicated with severe infection; (5) Patients with severe primary diseases of brain, lung, heart and liver system. 2. Healthy control group: (1) Abnormal results of physical examination report; (2) Chronic medical history such as hypertension, hyperlipidemia and diabetes; (3) Pregnant or lactating patients.

Design outcomes

Primary

MeasureTime frame
Total cholesterol;Triglycerides;Serum albumin;Urea nitrogen;Blood creatinine;24 hour urine protein quantification;

Countries

China

Contacts

Public ContactZheng Jiaxin

Heilongjiang Academy of Chinese Medicine

zjxemail@163.com+86 15045809666

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026