Gestational diabetes mellitus
Conditions
Interventions
Intervention group:Individualized nutritional intervention based on ''Eastern health dietary pattern'' and wearable device-based exercise intervention
Control group:Routine prenatal examination
Sponsors
Hospital of Obstetrics and Gynecology, Fudan University
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Pregnant women need to be examined and delivered in Obstetrics and Gynecology Hospital Affiliated to Fudan University or other sub-central hospitals. 2. The high risk group of GDM was selected by GDM prediction model. 3. The gestational age of the group was not more than 10 weeks + 6 days. 4. Aged >= 18 years. 5. Pregnant women have the ability to read, understand and sign informed consent forms. 6. Single pregnancy.
Exclusion criteria
Exclusion criteria: 1. Prepregnancy diabetes mellitus (PGDM), including diabetes diagnosed before pregnancy or fasting blood glucose >=7.0mmol/L or glycosylated hemoglobin (HbA1c) >=6.5% in early pregnancy, or typical hyperglycemic symptoms, or hyperglycemic crisis symptoms with arbitrary blood glucose value >=11.1 mmol/L. 2. Other cases of abnormal glucose tolerance, including fasting blood glucose >=5.6mmol/L in the first trimester. 3. Currently or recently taking drugs that affect glucose metabolism (such as metformin, glucocorticoids, etc.). 4. Severe complications, such as hypertension, heart disease, kidney disease, autoimmune disease, thyroid dysfunction, mental illness, past or present malignant tumor, etc. 5. Known severe fetal malformations or chromosomal abnormalities. 6. Cervical insufficiency, including cervical length < 25mm as measured by ultrasound before 24 weeks of this pregnancy, or history of spontaneous preterm labor at 14 to 36 weeks of previous pregnancy, or cervical dilation found in the past or during this pregnancy. 7. Other movement contraindication syndromes: persistent vaginal bleeding, threatened premature delivery, placenta previa, premature rupture of membranes, severe anemia, FGR, etc. 8. Drug abuse.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of GDM; | — |
Secondary
| Measure | Time frame |
|---|---|
| Maternal pregnancy outcome;Neonatal outcome;Maternal biochemistry indicators of glucose and lipid metabolism;Cord blood indicators of glucose and lipid metabolism;Edinburgh Postnatal Depression Scale Score; | — |
Countries
China
Contacts
Public ContactHuang Hefeng
Hospital of Obstetrics and Gynecology, Fudan University
Outcome results
None listed