Effect of Gender Factors on ED50 of Remazolam Combined with Sufentanil for Endotracheal Intubation in Elderly Patients Undergoing Hepatectomy

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200065725

Enrollment

Unknown

Registered

2022-11-14

Start date

2022-11-04

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Elderly male group:Injecting Remazolam by Dixon Modified Sequential Method

Elderly women group:Injecting Remazolam by Dixon Modified Sequential Method

Eligibility

Sex/Gender

All

Age

60 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged 60-80 years; 2. Liver resection for non-emergency patients; 3. BMI 19-24 kg/m^2; 4. Patients were informed about the study and signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Asthma; 2. Suspected difficult airway (Mallampati grade>=3, ankylosing spondylitis, etc.); 3. Sleep apnea syndrome; 4. Gastroesophageal reflux; 5. Have a full stomach; 6. Patients with drug and alcohol abuse and long-term benzodiazepine use; 7. Severe respiratory or cardiovascular diseases; 8. With an allergic reaction to any of the drugs involved.

Design outcomes

Primary

Measure	Time frame
Successful endotracheal intubation;	—

Secondary

Measure	Time frame
Heart rate and blood pressure at 4 time points;Postoperative sore throat;Postoperative hoarseness;Bad memory;	—

Countries

China

Contacts

Public ContactZhou Ling

The First Affiliated Hospital of University of Science and Technology of China (Anhui Provincial Hospital)

13866702756@163.com+86 13866702756

Outcome results