Sudden deafness
Conditions
Interventions
Experimental group:Conventional treatment of sudden deafness+ hydrogen-oxygen gas mixture inhalation treatment
Control group:Conventional treatment of sudden deafness
Sponsors
Yangpu Hospital, Tongji University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-70 years, no gender limit; 2. Meet the diagnostic criteria of sudden sensorineural hearing loss(Referring to the Guidelines for the Diagnosis and Treatment of Sudden Deafness (2015)): sudden sensorineural hearing loss with unknown cause within 72 hours, with a decrease in hearing of >= 20 dBHL affecting at least 2 consecutive frequencies; 3. Onset within 2 weeks; 4. Monomaural lesions; 5. Patients have good adherence and sign an informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with middle ear lesions, Meniere's disease, acoustic neuroma and other lesions; 2. History of ototoxic drug use; 3. Critical organ failure or other serious diseases (including myocardial infarction, severe myocardial lesions and refractory heart failure within 12 months prior to enrollment; Severe neurological disease: severe cerebral infarction, intracranial hemorrhage, or increased intracranial pressure within 12 months prior to enrollment; severe liver failure; severe renal failure; with bleeding disorders or bleeding tendencies); 4. Pregnant or lactating patients; 5. Patients who have participated in any other clinical trial of drugs or medical devices within 3 months prior to enrollment; 6. Patients deemed unsuitable for inclusion by the investigator for other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Threshold of Pure Tone Audiometry; | — |
Secondary
| Measure | Time frame |
|---|---|
| Tinnitus Disability Assessment Scale (THI);Visual Analog Scale (VAS) Score of Vertigo;Laboratory Tests; | — |
Countries
China
Contacts
Public ContactLiu Huiru
Yangpu Hospital, Tongji University School of Medicine
Outcome results
None listed