Breast Cancer
Conditions
Interventions
YXTZs exposure group:Yin Xing Tong Zhi tables 1# tid po. total 12weeks
nonexposed group:preoperative chemotherapy and/or radiotherapy, as well as postoperative biological agents after surgery, according to the National Comprehensive Cancer Network
Sponsors
Longhua Hospital affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Breast cancer is clearly diagnosed by pathological examination, and the pathological stage is stage I~III; 2. Patients who receive anthraline sequential/combined purple shirt regimen (neoadjuvant) chemotherapy for the first time after surgery with standard regimen and dose, within 1 year from the time of initial chemotherapy; 3. No recurrence and metastasis and intracranial abnormalities; 4. General cognitive function is normal, daily living ability is basically normal, no hearing, vision, language and other functional disorders, Karl Fischer score = 60 points; 5. Female patients aged 18-65 (including 18 and 65 years old); Willingness to undergo treatment, observation and examinations.
Exclusion criteria
Exclusion criteria: 1. Patients with dementia (MES screening scale 50 points), depression (SDS screening scale score greater than 53 points) and other psychiatric symptoms after screening by doctors with neuropsychological professional qualifications; 2. Patients with an estimated survival time of < 6 months; 3. Patients with serious primary diseases of cardiovascular and cerebrovascular, liver, kidney, and hematopoietic systems; 4. Women who are nursing, pregnant or planning to become pregnant; 5. History of alcohol or drug dependence, taking related drugs that affect cognition; 6. Allergic constitution and allergic to a variety of drugs; 7. Subjects who are participating in clinical studies of other drugs.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| FACT-cog;TCM evaluation of breast cancer depressive symptoms;Karnofsky, KPS; | — |
Primary
| Measure | Time frame |
|---|---|
| Incidence of memory and executive impairment;Event correlation potential P300; | — |
Countries
China
Contacts
Public ContactLiu Sheng
Department of Breast Surgery (Integrated Traditional and Western Medicine), Longhua Hospital affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed