radiation-induced oral mucositis
Conditions
Interventions
Case series:N/A
Sponsors
Affiliated Hospital of Jiangnan University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: ?newly diagnosed head and neck tumors by pathology;?Receive radiation therapy and the total dose was 60-70Gy;?AJCC 8th stage I-IVB without any distant metastases;?Age 18-75 years old; ?ECOG score =1;?Normal blood count, liver and kidney function;?No antibiotics, hormones or immune preparations and probiotics within 4 weeks before treatment;?No dentures or dentures have been removed and agreed to be enrolled and signed informed consent.
Exclusion criteria
Exclusion criteria: ? Palliative care; ? previous tumor disease; ? Pregnancy or lactation;? previous radiotherapy for tumor; ? suffering from oral mucositis or senile dry oral mucositis; ? suffering from other serious diseases; ? history of peptic ulcer, irritable bowel syndrome, inflammatory bowel disease, gastrointestinal malignancy and other gastrointestinal diseases; ? history of dental disease and oral examination revealed any active gum or periodontal disease; ? individuals with special diets; ? individuals treated with oral or fecal microbiota transplantation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| radiation-induced oral mucositis;patient-generated subjective nutrition assessment(PG-SAG);nutritional risk screening 2002 (NRS2002); | — |
Secondary
| Measure | Time frame |
|---|---|
| hemoglobin;albumin;prealbumin;total protein; | — |
Countries
China
Contacts
Public ContactJianfeng Huang
Affiliated Hospital of Jiangnan University
Outcome results
None listed