The value of confocal laser endoscopy combined with frozen lung biopsy in the diagnosis of interstitial lung disease

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200065688

Enrollment

Unknown

Registered

2022-11-11

Start date

2022-11-20

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Interstitial lung disease

Interventions

Experience group(CLE group):CLE exploratory imaging assisted biopsy

Control group (fluoroscopy group):X-ray fluoroscopy assisted biopsy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Thoracic HRCT showed diffuse diseases in both lungs, such as nodular shadows, ground glass shadows, patch consolidation shadows, fibrous grid-like, honeycomb shadows diffuse in both lung fields or most lung fields; 2. ILD patients who do not smoke (at least 3 months) and whose cause cannot be determined by comprehensive chest HRCT, clinical history, and routine examination methods (such as sputum examination, blood examination, routine tracheoscopy, etc).

Exclusion criteria

Exclusion criteria: 1. There are contraindications of routine bronchoscopy; 2. Partial blood oxygen pressure of low flow oxygen inhalation artery<60mmHg and nitric oxide diffusion volume (DLco) measured by one breath method of pulmonary function<30% predicted value.

Design outcomes

Primary

Measure	Time frame
Pathological positive diagnosis rate;	—

Secondary

Measure	Time frame
Maximum cross-sectional area of specimen;Operation time;complication;	—

Countries

China

Contacts

Public ContactCuiyun Zuo

The Second Affiliated Hospital of Xiamen Medical College

lry20101103@126.com+86 13656013359

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026