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FTO regulates the stability of CDH12 mrna through M6A modification to inhibit the invasion and metastasis of thyroid carcinoma

FTO regulates the stability of CDH12 mrna through M6A modification to inhibit the invasion and metastasis of thyroid carcinoma

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200065674
Enrollment
Unknown
Registered
2022-11-11
Start date
2022-11-20
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid cancer

Interventions

Thyroid cancer group :cllecting tissues of thyroid cancer
Thyroid normor group:cllecting Para-cancerous tissues of thyroid

Sponsors

The First Affiliated Hospital of University of South China
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients who had undergone thyroid surgery for the first time and had undergone lymph node dissection in Central District or neck dissection at the same time; 2. The diagnosis of thyroid thyroid cancer was confirmed by intraoperative frozen section and postoperative pathology; 3. No history of chemotherapy, radiotherapy and immunotherapy was found before operation.; 4. Age ranged from 18 to 80 years.

Exclusion criteria

Exclusion criteria: 1. Recurrent thyroid cancer; 2. Complicated with other malignant tumor; 3. Pregnant and breast-feeding women.

Design outcomes

Primary

MeasureTime frame
Fat mass and obesity-associated protein, FTO;IGF2BP2;CDH12;—

Countries

China

Contacts

Public ContactZuyao Chen

The First Affiliated Hospital of University of South China, Hengyang, Hu'nan, China

chenzuyao@usc.edu.cn+86 15116840899

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026