Gastric mucosal precancerous lesions
Conditions
Interventions
Non-atrophic gastritis group:Three pieces of gastric mucosal tissue, one drop of fingertip blood, and 10g of stool samples were collected
Atrophic gastritis with intestinal metaplasia group:Three pieces of gastric mucosal tissue, one drop of fingertip blood, and 10g of stool samples were collected
Sponsors
Xinqiao Hospital, Army Military Medical University
Eligibility
Sex/Gender
All
Age
30 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age: 30-75 years old; 2. Gender: male or female; 3. Diagnostic criteria: endoscopic diagnosis of atrophic gastritis with intestinal metaplasia or chronic non-atrophic gastritis; 4. Patients voluntarily participated in this study.
Exclusion criteria
Exclusion criteria: 1. Cardiovascular diseases, coagulation disorders, metabolic diseases and mental diseases (hypertension, diabetes, depression, etc.); 2. Taking antibiotics or probiotics in the past 3 months; 3. History of alcoholism, smoking and other tumors; 4. Those who are pregnant or lactating; 5. Previous history of esophageal or gastrointestinal surgery; 6. Other reasons are not suitable for painless endoscopy; 7. Persons who refused to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The HE dye;Carbon 13 breath test system;Rapid urea's test;Serum antibodies against Helicobacter pylori bacilli;untoward effect; | — |
Secondary
| Measure | Time frame |
|---|---|
| Helicobacter pylori bacillus antigen in stool;qPCR;Detection of CagA in gastric mucosal DNA;Immunofluorescence staining; | — |
Countries
China
Contacts
Public ContactYang shiming
Xinqiao Hospital, Army Military Medical University
Outcome results
None listed