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Effects of repetitive transcranial magnetism stimulation (rTMS) intervention on Electroencephalography (EEG) resting-state power spectra and functional connectivity in stroke patients with low upper limb function

Effects of repetitive transcranial magnetism stimulation (rTMS) intervention on Electroencephalography (EEG) resting-state power spectra and functional connectivity in stroke patients with low upper limb function

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200065639
Enrollment
Unknown
Registered
2022-11-10
Start date
2022-11-30
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

intervention group:LF-rTMS
control group:HF-rTMS

Sponsors

The Hong Kong Polytechnic University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 88 Years

Inclusion criteria

Inclusion criteria: 1. The first episode was diagnosed as a unilateral ischemic stroke; 2. The stroke condition was stable and did not continue to deteriorate; 3. The infarct lesion location was determined by imaging and was classified as cortical, subcortical, or cortico-subcortical; 4. Age >= 18 years, Right-handedness; 5. Upper extremity function assessed by the Functional Test for the Hemiplegic Upper Extremity (FTHUE-HK) with 2 – 4 level; 6. Experienced rehabilitation after stroke; 7. Have the ability to communicate normally and understand simple verbal instructions; 8. Able to understand and voluntarily sign a written consent form to participate in the study.

Exclusion criteria

Exclusion criteria: 1. Hemorrhagic stroke; 2. Previous diagnosis of a neurological disorder besides stroke; 3. Severe aphasia or Presence of cognitive impairment that affects comprehension of instructions, Mini-Mental State Examination(MMSE)<= 2173 74; 4. Presence of pain that prevents completion of functional assessment; 5. Impaired function due to upper limb injury caused by other diseases rather than stroke; 6. Contraindications to rTMS.

Design outcomes

Primary

MeasureTime frame
resting-state EEG;

Secondary

MeasureTime frame
National Institute of Health stroke scale;Fugl–Meyer Assessment upper Extremity;Modified Barthel Index;

Countries

China

Contacts

Public ContactSam C. C. Chan

Department of Rehabilitation Sciences The Hong Kong Polytechnic University

samcc.chan@polyu.edu.hk+86 852 2766 4310

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 18, 2026