Skip to content

To compare the hemodynamic effects of remimazolam besylate and propofol during cervical dilatation in obstetrics and gynecology surgery

To compare the hemodynamic effects of remimazolam besylate and propofol during cervical dilatation in obstetrics and gynecology surgery

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200065624
Enrollment
Unknown
Registered
2022-11-10
Start date
2021-11-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dilatation and curettage / hysteroscopy surgery

Interventions

Group R (Patients undergoing aspiration curettage):remimazolam
Group R (Patients undergoing aspiration curettage):Propofol
Group PR (Patients undergoing aspiration curettage):Remimazolam+Propofol
Group J (Patients undergoing aspiration curettage):lidocaine
Group RG (Patients undergoing hysteroscopy):remimazolam
Group PG (Patients undergoing hysteroscopy):Propofol

Sponsors

Fuzhou Jin'an District Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 48 Years

Inclusion criteria

Inclusion criteria: 1. Age 18 ~ 48 years old; 2. Weight 18-30 kg/m^2; 3. The American Society of anesthesiologists (ASA) classification is I ~ II level; 4. There was no previous history of spontaneous vaginal delivery; 5. Consent and signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients with a long history of taking sedative and analgesic drugs or drug use or alcohol abuse before operation; 2. Patients with arrhythmia, cardiovascular disease, diabetes, thyroid disease, and autonomic nerve dysfunction; 3. Allergic to drugs and excipients; 4. Sleep apnea syndrome or difficult airways; 5. Recent respiratory infections; 6. Communication difficulties; 7. Other researchers think it is not possible to include the situation.

Design outcomes

Primary

MeasureTime frame
Vital signs;acetylcholine;

Secondary

MeasureTime frame
Heart rate variability;Adverse reactions;

Countries

China

Contacts

Public ContactZhang Haimei

Fuzhou Jin 'an District Hospital

13959141539@163.com+86 13959141539

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026