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Increased Prefrontal activation during verbal fluency task compared to non-insomniacs: A study using Functional Near-Infrared Spectroscopy in depressed patients

Increased Prefrontal activation during verbal fluency task compared to non-insomniacs: A study using Functional Near-Infrared Spectroscopy in depressed patients

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200065622
Enrollment
Unknown
Registered
2022-11-10
Start date
2022-11-21
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The major depression

Interventions

Control group:N/A
Somnipathy group:N/A
Depression group 1:N/A
Depression group 2:N/A

Sponsors

8 Beijing Road, Yunyan District, Guiyang, Guizhou
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Criteria for admission to the depression group (1) Age: 18-60 years old; (2) Meet the diagnostic criteria of DSM-5 moderate major depressive disorder; (3) HAMD > 17 points; (4) Have not taken antidepressants and hypnotic drugs in the past three months; (5) Voluntarily participate in experiments; (6) Understand the research content and sign an informed consent form; (7) Right hand 2. Admission criteria for sleep disorder groups (1) Age: 18-60 years old; (2) Meet the diagnostic criteria for sleep disorders in DSM-5; (3) Have not taken antidepressants and hypnotic drugs in the past three months; (4) Voluntarily participate in experiments; (5) Understand the research content and sign informed consent; (6) Right hand; 3. Normal group enrollment criteria (1) Age: 18-60 years old; (2) Volunteer to participate in the experiment; (3) Have not taken antidepressants and hypnotic drugs in the past three months; (4) Understand the research content and sign an informed consent form; (5) Right hand.

Exclusion criteria

Exclusion criteria: 1. Criteria for exclusion in the depression group (1) Have suffered from other mental disorders in DSM-5 (such as schizophrenia spectrum and other psychotic disorders, bipolar and related disorders, anxiety disorders, obsessive-compulsive and related disorders, trauma and stress-related disorders, etc.); (2) Substance abuse, dependence; (3) Pregnant or lactating women; (4) Those who have serious physical diseases (such as coronary heart disease, hypertension, chronic bronchitis, pneumonia, diabetes, etc.); (5) Accompanied by obvious impulsive behavior and cannot cooperate with the examiner. 2. Exclusion criteria for the sleep disorder group (1) Have suffered from other mental disorders in DSM-5 (such as schizophrenia spectrum and other psychotic disorders, bipolar and related disorders, anxiety disorders, obsessive-compulsive and related disorders, trauma and stress-related disorders, etc.); (2) Substance abuse, dependence; (3) Pregnant or lactating women; (4) Have serious medical diseases (such as coronary heart disease, hypertension, chronic bronchitis, pneumonia, diabetes, etc.); (5) Accompanied by obvious impulsive behavior, cannot cooperate with the examination. 3. Normal group exclusion criteria (1) Have suffered from mental disorders in DSM-5 (such as schizophrenia spectrum and other psychotic disorders, bipolar and related disorders, anxiety disorders, obsessive-compulsive and related disorders, trauma and stress-related disorders, etc.); (2) Substance abuse, dependence; (3) Pregnant or lactating women; (4) Have serious medical diseases (such as coronary heart disease, hypertension, chronic bronchitis, pneumonia, diabetes, etc.); (5) Accompanied by obvious impulsive behavior, cannot cooperate with the examination.

Design outcomes

Primary

MeasureTime frame
Hemoglobin concentration;

Countries

China

Contacts

Public ContactWang Yiming

The Affiliated Hospital of Guizhou Medical University

Yimingw66@yahoo.com+86 13511967666

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 11, 2026