port wine stain
Conditions
Interventions
Control group:532nm light
Intervention Group:532nm + 630nm light
Sponsors
Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University, School of Medicine
Eligibility
Sex/Gender
All
Age
14 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients who meet the port-wine stain diagnostic criteria of the Guidelines for the Diagnosis and Treatment of hemangioma and vascular malformation (2019 edition); 2. Aged between 14 and 65; 3. Simple PWS and related syndromes include SW syndrome (SWS), Phakomatosis pigmentovascularis (PPV), etc. The erythema is required to be relatively isolated from other lesions of the syndrome, that is, there is no other related dermatological changes in the erythema site, such as dermal melanocytosis, etc.; 4. No scar was left after receiving other treatment for more than 3 months; 5. After fully understanding the treatment plan and risks, I or my guardian voluntarily signed the informed consent, willing to accept the clinical trial and cooperate with follow-up.
Exclusion criteria
Exclusion criteria: 1. Patients with original infection, eczema, ulcer and other lesions that may affect the therapeutic effect and with other pigmented diseases such as nevus ota; 2. The patient has a history of epileptic seizures in the last six months or the condition is not controlled; 3. Allergic to porphyrins and analogs, allergic constitution; 4. There is a scar constitution; 5. A history of sun exposure in the last 3 months; 6. Patients with ECG abnormalities, organic heart disease, abnormal liver function, pregnant women or women with pregnancy plans, and other potential diseases that may affect treatment; 7. Is participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| visual analogue scale; | — |
Countries
China
Contacts
Public ContactGang Ma
Shanghai Ninth People's Hospital, Shanghai Jiao Tong University, School of Medicine
Outcome results
None listed