Melasma
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. 18-60 years old, female; 2. Clinically diagnosed as chloasma patients, accompanied by thick pores or wrinkles; 3. Melasma lesions are bilateral and symmetrical; 4. Signed informed consent;
Exclusion criteria
Exclusion criteria: 1. There are other severe facial spots or pigmentation, which may affect the efficacy evaluation; 2. Similar treatment or clinical trial within the last 3 months; 3. Recent exposure history; 4. Photosensitive or used photosensitive drugs within 2 weeks; 5. Pregnant women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Grade of melasma improvement;Melasma area severity index,MASI; | — |
Secondary
| Measure | Time frame |
|---|---|
| VISIA score; | — |
Countries
China
Contacts
Shanghai Ninth People's Hospital, Shanghai Jiao Tong University, School of Medicine