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Combined intravenous lidocaine and Nociception Level (NOL) index improve pulmonary function after video-assisted thoracoscopic surgery: a randomized double-blind controlled trial

Effect of combined intravenous lidocaine and Nociception Level (NOL) index monitoring on pulmonary function after video-assisted thoracoscopic surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200065605
Enrollment
Unknown
Registered
2022-11-09
Start date
2022-11-15
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Video-assisted thoracoscopic surgery

Interventions

Control group:Intravenous anesthesia + normal saline
Experimental group:Intravenous anesthesia + lidocaine

Sponsors

Sun Yat-sen University Cancer Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Signed informed consent; Patients undergoing elective thoracoscopic segmentectomy or lobectomy; ASA ?-?; Aged 18-75 years.

Exclusion criteria

Exclusion criteria: Refused to participate in the study; BMI= 35kg/m^2; Allergy to local anesthetics; Baseline FEV1< predicted value 30%; Severe lung or heart diseases; Liver or kidney failure; Patients with a history of mental illness or who are unable to cooperation; Pregnancy or lactation.

Design outcomes

Primary

MeasureTime frame
FEV1;—

Secondary

MeasureTime frame
Pain score;Opioids consumption;Quality of recovery;Complication;Postoperative pulmonary complications;Pulmonary function;—

Countries

China

Contacts

Public ContactQiang Li

Sun Yat-sen University Cancer Center

liqiang@sysucc.org.cn+86 15918482688

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026