Malignant solid tumors
Conditions
Interventions
Sponsors
The First Medical Center of Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 75 years, male or female; 2. Subjects with histopathologically confirmed malignant solid tumor; 3. Subjects with definite measurable lesions; 4. Subjects or the guardian agree to participate in the clinical trial and sign the Informed Consent Form before enrollment.
Exclusion criteria
Exclusion criteria: 1. Subjects with a history of organ transplantation; 2. Subjects that have received adjuvant therapy since diagnosis (eg: chemotherapy, radiotherapy or immunotherapy); 3. Subjects with any other serious disease within 5 years except cured skin cancer and in situ cervical cancer; 4. Have received or is undergoing any other clinical drug study, other gene therapy or cell therapy; 5. Pregnant or lactating women; 6. Any uncontrollable active infection; 7. HIV positive; 8. Treponema pallidum positive; 9. HCV positive; 10. Subjects who are using immunosuppressive drug or steroids, those using inhaled steroids recently are not excluded; 11. Subjects with primary immunodeficiency or bone marrow deficiency; 12. Poor compliance or unsuitable for the clinical trial according to investigators; 13. Other: Subjects are not suitable for the study judged by investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cell number of TIL in tissue;function of TIL in tissue; | — |
Secondary
| Measure | Time frame |
|---|---|
| subset of TIL in tissue; | — |
Countries
China
Contacts
Public ContactXiao Zhao
The First Medical Center of Chinese PLA General Hospital
Outcome results
None listed