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Diagnosis and application value of peripheral blood small non-coding RNA (sncRNA) in patients with sepsis

Diagnosis and application value of peripheral blood small non-coding RNA (sncRNA) in patients with sepsis

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200065592
Enrollment
Unknown
Registered
2022-11-09
Start date
2022-11-15
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Interventions

Gold Standard:The consensus of the 2016 International Conference on Sepsis.
Index test:specific small non-coding RNA content

Sponsors

Third Xiangya Hospital, Central South University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. The diagnosis criteria of sepsis and septic shock were in line with the consensus of the 2016 International Conference on Sepsis. 2. Survival time >= 24 hours after admission. 3. Age >= 18 years. 4. Sign the informed consent. 5. Patients with common infection: (1) infection on admission (including evidence of infection provided by clinical physical examination, imaging examination or laboratory positive results, such as visceral perforation, white blood cells in sterile body fluids, lung infection shown by chest radiograph or CT, etc.), satisfying the diagnosis of SIRS. (2) It does not meet the diagnostic criteria of sepsis.

Exclusion criteria

Exclusion criteria: 1. Admission time <24 hours. 2. Age <18 years old. 3. Suffering from tumor or immune or hematological diseases. 4. Previous sepsis or severe infection. 5. Pregnant or lactating patients. 6. Incomplete clinical data.

Design outcomes

Primary

MeasureTime frame
sncRNA;

Countries

China

Contacts

Public ContactChuanzheng sun

Third Xiangya Hospital, Central South University

sunchuanzheng@csu.edu.cn+86 13574841516

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026