Migraine
Conditions
Interventions
Simple menstrual migraine:None
Menstrual related migraine:None
menstrual-unrelated migraine:None
Health female:None
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Female, 18-50 years old, right-handed; 2. Conforming to the standard of migraine without aura, and the course of disease is more than one year; 3. The menstrual cycle is 28 ± 7 days; 4. Menstrual migraine requires migraine to occur within 1 ± 2 days of at least two cycles in every three menstrual cycles; 5. The menstrual-unrelated migraine group only had migraine attacks outside the menstrual period
Exclusion criteria
Exclusion criteria: 1. MRI showed brain lesions; 2. Suffering from nervous system disease, severe anxiety or depression; 3. MRI contraindications such as claustrophobia and metal implants; 4. History of alcohol or drug abuse; 5. During pregnancy or lactation; 6. Those who have severe cognitive impairment and are unable to cooperate in completing the experiment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Functional MRI;Genomics;Structural MRI;Saccade characteristics;severity of headache;Headache frequency; | — |
Secondary
| Measure | Time frame |
|---|---|
| Headache Impact Test (HIT-6);Migraine Disability Assessment (MIDAS);Neuropsychological tests;Proteomics;metabolomics; | — |
Countries
China
Contacts
Public ContactChen Lei
West China Hospital, Sichuan University
Outcome results
None listed