Rotator cuff tear
Conditions
Interventions
RANKL monoclonal antibody treatment group:RANKL monoclonal antibodies + VitD3 + calcium carbonate
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
Female
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients with full-thickness rotator cuff tear or Elman type III partial tear treated with arthroscopic surgery; age >= 50 years; female.
Exclusion criteria
Exclusion criteria: Huge rotator cuff tear; Concomitantly clear shoulder stiffness; Smokers; Diseases of the immune system; Diseases of the hematologic system; Tumor patients; Various metabolic bone diseases, such as osteogenesis imperfection and osteomalacia; Malabsorption syndrome or various gastrointestinal disorders associated with malabsorption; Hypocalcemia or hypercalcemia, or serum albumin-corrected blood calcium levels that are not within the normal laboratory values; Vitamin D deficiency; Suffering from severe liver and kidney diseases; Previous drugs anti-osteoporosis patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| BMD (bone mineral density);MRI of shoulder;the university of California at Los Angeles shoulder rating scale (UCLA);visual analogue scale (VAS);The Constant-Murley score (CMS); | — |
Secondary
| Measure | Time frame |
|---|---|
| C-telopeptide of crosslinked collagen type II (CTX-II);Procollagen type I N-terminal propeptide (P1NP); | — |
Countries
China
Contacts
Public ContactXin Tang
West China Hospital, Sichuan University
Outcome results
None listed