Preoperative sedation of children
Conditions
Interventions
M group:0.75mg/kg oral midazolam
D group:2ug/kg intranasal dexmedetomidine
MD group: 0.75mg/kg oral midazolam plus 1ug/kg intranasal dexmedetomidine
Sponsors
The Second Affiliated Hospital of Shantou University Medical College
Eligibility
Sex/Gender
All
Age
2 Years to 6 Years
Inclusion criteria
Inclusion criteria: 1. ASA physical status I or II 2. aged 2-6 years 3. Lower abdomen or perineum surgery, the operation time is less than 60 minutes 4. BMI 18.5-23.9 5. The guardian of the child is informed of the study and signs the informed consent form
Exclusion criteria
Exclusion criteria: 1. known allergic to benzodiazepines, opioids, dexmedetomidine, propofol 2. respiratory infections 3. patients with severe heart, brain, liver, kidney and metabolic diseases 4. emergency surgery 5. gastrointestinal diseases 6. nasal mucosa injury
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| satisfactory sedation rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| onset time;Ramsay sedation scale;satisfactory induction rate;Wake Up Time;incidence of PAED; | — |
Countries
China
Contacts
Public ContactYongfa Zhang
The Second Affiliated Hospital of Shantou University Medical College
Outcome results
None listed