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Effect of ropivacaine combined with betamethasone in local infiltration anesthesia on acute and chronic pain after thoracoscopic surgery: a multicentre, prospective, randomized controlled trial

Effect of ropivacaine combined with betamethasone in local infiltration anesthesia on acute and chronic pain after thoracoscopic surgery: a multicentre, prospective, randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200065565
Enrollment
Unknown
Registered
2022-11-08
Start date
2022-11-07
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute and chronic pain after thoracoscopy

Interventions

BR:Ropivacaine in combination with betamethasone
B:betamethasone
C:0.9%saline

Sponsors

Fujian Medical University Union Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 79 Years

Inclusion criteria

Inclusion criteria: 1. Elective thoracoscopic surgery 2. Age from 18-79 years old 3. American Society of Anesthesiologists (ASA) Grades I-III 4. Body mass index (BMI) 20-28kg/m2 5. Mentally competent, able to correctly understand NRS scores and correctly assess pain levels

Exclusion criteria

Exclusion criteria: 1. Severe cardiovascular disease (uncontrolled hypertension, congestive heart failure, severe angina attack, or previous unstable angina or myocardial infarction within 6 months) 2. With liver or kidney disease (alanine aminotransferase, portal aminotransferase or both > 40 U/L ;blood creatinine > 133 mmol/L) 3. Have diabetes 4. History of peptic ulcers or gastrointestinal bleeding 5. Hypersensitivity to ropivacaine, betamethasone, dexmedetomidine 6. History of chronic pain, long-term use of sedative and analgesic drugs 7. Contraindications to nerve blocks and paravertebral blocks 8. Intraoperative open-heart patient 9. Previous open-heart surgery 10. Unable to cooperat

Design outcomes

Primary

MeasureTime frame
NRS score (resting, cough, active);Incidence of postoperative pain;

Secondary

MeasureTime frame
Pain Description;The effect of pain on body function;Postoperative analgesia;Adverse reactions;Blood tests;

Countries

China

Contacts

Public ContactZhongmeng Lai

Fujian Medical University Union Hospital

angerer1980@163.com+86 13395000771

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026