acute circulatory failure
Conditions
Interventions
Gold Standard:Fluid responsiveness was defined as an increase >10% in velocity-time integral (measured by TTE) after PLR test
Index test:Decrease in pulse pressure variation after passive leg raising, velocity-time integral variation, peak velocity variation, pulse pressure variation
Sponsors
The First Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: The critically ill patients in mechanically ventilated patients with spontaneous breathing occur one or more of the following symptom(s) of acute circulatory failure: systolic blood pressure (SBP) 2 mmol/L); tachycardia (heart rate >100 beats per minute), and mottling of the skin
Exclusion criteria
Exclusion criteria: age <18 years, left ventricular (LV) dysfunction (ejection fraction <40%), intracranial hypertension, active bleeding, intra-abdominal hypertension, arrhythmia, lower limbdisability, pregnant women, a contraindication to the PLR maneuver, the echocardiography could not be gained and poor echogenicit
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pulse pressure variation;maximal velocity-time integral;minimal velocity-time integral;maximal peak velocity;minimal peak velocity;velocity-time integral; | — |
Secondary
| Measure | Time frame |
|---|---|
| central venous pressure;heart rate;mean arterial pressure; | — |
Countries
China
Contacts
Public ContactJin Xie
The First Affiliated Hospital of Soochow University
Outcome results
None listed