Intestinal diseases
Conditions
Interventions
Esketamine group:Esketamine 0.2 mg/kg
Control group:Identical volume of saline
Sponsors
Fujian Provincial Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age 18–75 years; 2. American Society of Anesthesiologists (ASA) 1 to 3; 3. Scheduled for outpatient colonoscopy.
Exclusion criteria
Exclusion criteria: 1. patient refusal to participate. 2. BMI greater than 30; 3. allergic or contraindication to study drugs; 4. inability to ambulate without assistance; 5. Required therapeutic endoscopies, such as endoscopic mucosal resection or endoscopic submucosal dissection; 6. History of psychiatric illness; 7. History of neurological disease; 8. History of seizure disorders; 9. history of medication or alcohol abuse 10. any other conditions that precluded study inclusion, such as cognitive impairment, pregnancy, or inability to communicate in Mandarin Chinese.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of patients ready for discharge within postoperative 30 min; | — |
Secondary
| Measure | Time frame |
|---|---|
| Propofol consumption;Injection pain;Patient satisfaction;Patient willingness to repeat procedure;Endoscopist satisfaction;Induction time;Postoperative quality of recovery;Incidence of adverse effect;Emergency time;Patient willingness to recommend the procedure; | — |
Countries
China
Contacts
Public ContactYusheng Yao
Fujian Provincial Hospital
Outcome results
None listed