Hysteroscopic surgery
Conditions
Interventions
the propofol group:Intravenous propofol
the remazolam group :Intravenous remazolam
the remazolam+propofol group:Start with propofol, then remazolam
Sponsors
Weifang Maternal and Child Health Hospital
Eligibility
Sex/Gender
Female
Age
30 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Age between 30 and 50 years old. 2. Body mass index (BMI) 18–30 kg/m2. 3. American Society of Anesthesiologists (ASA) class I–II. 4. Patients underwent painless hysteroscopy and therapeutic surgery.
Exclusion criteria
Exclusion criteria: 1. Patients with respiratory or cardiac dysfunction. 2. Those suffering from severe hepatic or renal insufficiency, and neuropsychiatric diseases. 3. Patients with severe hypertension, and diabetes mellitus. 4. Patients who had a history of sedative and analgesic administration. 5. Those who were allergic or contraindicated to benzodiazepines, opioids, propofol, flumazenil, or naloxone. 6. Those who escalated to tracheal intubation and general anesthesia, a procedure time of more than 1 h, or an inability to communicate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the total incidence of adverse events; | — |
Secondary
| Measure | Time frame |
|---|---|
| the changes of perioperative mean arterial pressure;the changes of perioperative heart rate;the changes of perioperative saturation of peripheral oxygen;perioperative MOAAS sedation score;Recovery room time;Out of room sedation score;analgesia score after leaving the room;the examination time;the anesthesia recovery time ; | — |
Countries
China
Contacts
Public ContactJingjing zhang
Weifang Maternal and Child Health Hospital
Outcome results
None listed