Portal hypertension
Conditions
Interventions
Test group:alfentanil analgesia
control group:fentanyl PCA analgesia
Sponsors
The Second Affiliated Hospital of Hainan Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 807 Years
Inclusion criteria
Inclusion criteria: 1. The subject voluntarily signed the informed consent for this trial; 2. Aged between 18 and 80, male or female; 3. patients requiring transjugular intrahepatic portal shunt after diagnosis; 4. Patients or their nursing staff can fill in the survey form; 5. Correctly understand and cooperate with the medication guidance of medical staff; 6. American Society of Anesthesiologists (ASA) grade ?- ?; 7. ECOG-PS score 0 - 2.
Exclusion criteria
Exclusion criteria: 1. Severe valvular cardiac insufficiency or congestive heart failure; 2. uncontrollable systemic infection or inflammation; 3. End-stage liver disease score > 18 or Child-Pugh score > 13; 4. severe pulmonary hypertension; 5. pulmonary heart disease; 6. Chronic obstructive pulmonary disease; 7. severe renal insufficiency; 8. rapidly progressive liver failure; 9. Diffuse malignant tumor of liver; 10. Patients who are allergic to test drugs or any other excipients or contrast agents; 11. Patients with opioid addiction and alcoholism (definition); 12. Cognitive dysfunction; 13. patients with severe depression; 14. Did not participate in the drug test (including the drug under test) within 1 month before the test 15. Those who are deemed unsuitable for the study by the researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean value of NRS at time point of T1-T3 assessment; | — |
Countries
China
Contacts
Public ContactYong Wang
Interventional Radiology and Vascular Surgery, The Second Affiliated Hospital of Hainan Medical University
Outcome results
None listed