Study on the targeted treatment of prolonged disorders of consciousness with EEG nonlinear dynamic analysis

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200065470

Enrollment

Unknown

Registered

2022-11-05

Start date

2022-11-10

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

disorders of consciousness

Interventions

Test group:tDCS treatment

Control group:Routine rehabilitation

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. First brain trauma or cerebral hemorrhage; 2. The course of disease was 2-10 months; 3. Comply with the clinical diagnosis of UWS, MCS and EMCS; 4. Able to cooperate with EEG examination and tDCS treatment; 5. Sign the written informed consent.

Exclusion criteria

Exclusion criteria: 1. Unstable vital signs; 2. Obvious traffic or obstructive hydrocephalus; 3. Serious brain stem injury or injury is limited to the brain stem; 4. Severe convulsion (causing serious EMG interference); 5. There are contraindications to the treatment of tDCS (such as epilepsy, intracranial metal foreign bodies, skin damage at the stimulation site, etc.).

Design outcomes

Primary

Measure	Time frame
CRS-R, the Coma Recovery Scale-Revised;	—

Secondary

Measure	Time frame
EEG, electroencephalogram ;	—

Countries

China

Contacts

Public ContactXu Zhang

Wangjing Hospital of China Academy of Chinese Medical Sciences

zhangxu112452@163.com+86 13269669266

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026