dry eye disease
Conditions
Interventions
Gold Standard:1. OSDI score >= 13 points
2. BUT < 10 s.
Index test:AI measures fluorescein tear film break-up time
Sponsors
Eye Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-45 years; 2. Dry eye patients with BUT = 13 points; 4. Agree to participate in this trial, voluntarily test and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with other eye diseases that affect the normal formation of tear film, such as keratitis, corneal ulcer, corneal leukoplakia, corneal pannus, eye trauma, etc.; 2. Recent (within 3 months) history of eye surgery, including ocular surface and intraocular surgery; 3. Abnormal eyelid anatomy, such as incomplete closure, eyelid defect, proptosis, etc.; 4. Patients who are taking drugs that affect tear secretion; 5. Patients who are instilling other eye drops except for the treatment of dry eyes; 6. Any contact lens wearer; 7. Those who are allergic to sodium fluorescein; 8. Those with poor cooperation or unqualified data quality.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ocular Surface Disease Index (OSDI) Questionnaire;Fluorescein tear film break-up time;Fluorescein tear film break-up type;Corneal fluorescence staining;River of tears height;schirmer test;Meibomian gland assessment; | — |
Countries
China
Contacts
Public ContactJinyang Li
Eye Hospital of Wenzhou Medical University
Outcome results
None listed