Liver cirrhosis and complications
Conditions
Interventions
Gold Standard:AKI was diagnosed as a >= 26.5 umol/L increase in serum creatinine within 48 hours or a >= 50% increase in serum creatinine level from baseline within 7 days. In AKI stage 1, serum creat
In AKI stage
Index test:Urinary tissue inhibitor of matrix metalloproteinase-2 (TIMP-2), Insulin-like growth factor-binding protein 7 (IGFBP7), Urinary neutrophil gelatinase-associated lipocalin (NGAL), Urinary ki
Sponsors
Department of Infection, Changhai Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients hospitalized in Changhai Hospital for decompensation of liver cirrhosis; 2. Ability to understand and sign informed consent forms.
Exclusion criteria
Exclusion criteria: 1. Patients with severe advanced liver cancer or extrahepatic malignancy; 2. Patients with chronic kidney disease and structural kidney injury; 3. Patients with severe cardiopulmonary dysfunction; 4. Patients whose condition cannot be monitored during hospitalization due to liver transplantation, death from non-AKI, or other reasons; 5. Pregnant or lactating women; 6. The investigators believe there may be patients with poor compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Novel urinary biomarkers (NGAL, KIM-1, IGFBP7 and TIMP-2); | — |
Countries
China
Contacts
Public ContactLi Chengzhong
Changhai Hospital
Outcome results
None listed