Bronchopulmonary Dysplasia
Conditions
Interventions
Low-dose group:Vitamin D, 800 IU/d
Medium-dose group:Vitamin D, 1000 IU/d
High-dose group:Vitamin D, 1200 IU/d
Sponsors
Jinhua Maternity and Child Health Care Hospital, Zhejiang, China
Eligibility
Sex/Gender
All
Age
No minimum to 1 Years
Inclusion criteria
Inclusion criteria: Premature infants younger than 31 weeks of gestational age.
Exclusion criteria
Exclusion criteria: 1. Infants who have a birth weight of less than 3th percentile for gestational age; 2. Pregnant women or premature infants who have liver and/or kidney diseases; 3. Premature infants with severe congenital malformation, inherited metabolic disorders or chromosomal disorders; 4. Infants who develop necrotizing enterocolitis or spontaneous gastrointestinal perforation during treatment; 5. Individuals who fast for more than 3 days during treatment; 6. Those who stay in a hospital for less than 14 days; 7. Infants whose guardians decide to give up the treatment; 8. Infants whose guardians are unwilling to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum 25-OH vitamin D; | — |
Secondary
| Measure | Time frame |
|---|---|
| Parathyroid hormone;Urinary calcium / Creatinine;Alkaline phosphatase;Serum phosphorus;Serium calcium;Microbiome; | — |
Countries
China
Contacts
Public ContactYuan Gao
Jinhua Maternity and Child Health Care Hospital, Zhejiang, China
Outcome results
None listed