Early diagnosis of stomach cancer
Conditions
Interventions
Index test:1. Plasma gene methylation testing
2. Serum CEA/PGI/II/HP antibody detection
Sponsors
Zhongshan People's Hospital
Eligibility
Sex/Gender
All
Age
35 Years to 84 Years
Inclusion criteria
Inclusion criteria: 1. Have full behavioral capacity, Aged 35-84 years, regardless of gender; 2. Have already had gastroscopy, or gastroscopy/pathological examination results at our center, and agree to provide a blood sample within 1 week of gastroscopy.
Exclusion criteria
Exclusion criteria: 1. I have a history of gastric cancer surgery/chemotherapy/radiotherapy before enrollment; 2. Subjects who have received Helicobacter pylori treatment within four weeks before enrollment; 3. People with severe intellectual disabilities or language communication disorders, severe heart, brain, lung diseases or liver and kidney dysfunction; 4. Taking demethylation drugs (such as decitabine, azacitidine, hydralazine, procainamide, procaine, curcumin, etc.) within two months before enrollment; 5. Have received chemotherapy or taken antineoplastic drugs (eg, epirubicin, carboplatin, paclitaxel, cisplatin, fluorouracil, capecitabine, tegio, trastuzumab, etc.) prior to enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma gene methylation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Carcinoembryonic Antigen;Pepsinogen I;Pepsinogen II;Helicobacter pylori antibody; | — |
Countries
China
Contacts
Public ContactShijun Sun
Zhongshan People's Hospital
Outcome results
None listed