fibrobronchoscopy in elderly patients
Conditions
Interventions
remimazolam group:Administration of intravenous remimazolam
propofol group:Administration of intravenous propofol
Sponsors
The Affiliated Hospital, Hengyang Medical School, University of South China
Eligibility
Sex/Gender
All
Age
60 Years to 79 Years
Inclusion criteria
Inclusion criteria: 1. Aged >= 60 years, both sexes; 2. The ASA classification is I-III; 3. 18 kg/m2 or less a BMI of 30 kg/m2 or less; 4. Subjects who plan to undergo bronchoscopic diagnosis and/or treatment without assisted ventilation; 5. 10 times/min = 93%; SBP 90 MMHG or higher; DBP 55 MMHG or higher; 50 beats/min <= heart rate <= 100 beats/min; 6. Able to understand and voluntarily sign the informed consent (ICF), willing to comply with and expected to complete the trial in accordance with the protocol.
Exclusion criteria
Exclusion criteria: 1. Patients with contraindications of deep sedation/general anesthesia or with a history of sedation/anesthesia accidents; 2. Parazepines, opioids, propofol, flumazenil, naloxone, lidocaine and other drugs and their drug components Sensitive or taboo; 3. Patients who have been intubated and/or mechanically ventilated before bronchoscopy; 4. Gastrointestinal history: history of gastrointestinal retention, active bleeding, gastroesophageal reflux or obstruction, and assessment of the risk of regurgitation and aspiration; 5. History of nervous system: craniocerebral injury, intracranial hypertension, cerebral aneurysm, cerebrovascular accident; 6. Psychiatric history: patients with a history of schizophrenia, mania, psychosis, or cognitive dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| modified obsevers assessment of alertness/sedation scale (MOAA/S) assessment;Aldrete assessment;Blood Pressure;heart rate;respiratory rate;SpO2; | — |
Secondary
| Measure | Time frame |
|---|---|
| Start check time;End Check Time;remedies;Sufentanil and lidocaine use;remedies; | — |
Countries
China
Contacts
Public ContactChengda Zhao
The Affiliated Hospital, Hengyang Medical School, University of South China
Outcome results
None listed