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Effect of Different Administration Methods of Dexmedetomidine on Recovery in Children Receiving Tonsillectomy and Adenoidectomy

Effect of Different Administration Methods of Dexmedetomidine on Recovery in Children Receiving Tonsillectomy and Adenoidectomy

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200065404
Enrollment
Unknown
Registered
2022-11-03
Start date
2022-11-12
Completion date
Unknown
Last updated
2023-09-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Snoring in children

Interventions

Intravenous pumping group:After routine induction and intubation, intravenous infusion of 1 ug/kg dexmedetomidine was completed within 10 min
Control group:Routine anesthesia induction without dexmedetomidine
Nasal drip group:Dextrmedetomidine 2 ug/kg was intranasally administered after conventional induction intubation

Sponsors

Anhui Children's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 10 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1. Children with tonsillectomy and adenoidectomy at selected time; 2. Aged 3-10 years, ASA grade I-II; 3. No previous history of allergy to narcotic drugs; 4. First experience of surgery; 5. The operation time is 20-40 minutes.

Exclusion criteria

Exclusion criteria: Exclusion criteria: 1. Allergy to active ingredients or excipients of dexmedetomidine or similar substances; 2. History of bronchial or cardiovascular diseases, abnormal liver and kidney functions; 3. Moderate to severe obesity, with respiratory tract infection or nasal catarrh symptoms; 4. Used sedatives or a2 receptor agonists or antagonists, sinus bradycardia or atrioventricular block in the past; 5. Rejected by children's parents.

Design outcomes

Primary

MeasureTime frame
Incidence and severity of emergence agitation agitation;

Countries

China

Contacts

Public ContactZhao Xuemei

Anhui Children's Hospital

1622182358@qq.com+86 173 3309 3130

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026