stroke
Conditions
Interventions
experimental group:cerebellar vermis iTBS + conventional physical therapy
control group:sham stimulation + conventional physical therapy
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. A diagnosis of an ischemic stroke according to the Diagnostic criteria of cerebrovascular diseases in China (version 2019); 2. Aged 18-65 years; 3. First-ever unilateral ischemic stroke confirmed by imaging examination; 4. Subacute stroke participants with the stroke onset ranged from 2 weeks to 6 months; 5. Having motor deficit and balance dysfunction, with the Fugl-Meyer assessment scale score for lower extremities (FMA-LE) < 34 points and BBS score < 56 points.
Exclusion criteria
Exclusion criteria: 1. Diagnosis of coexisting other neurological diseases; 2. Injury of cerebellum or brain stem; 3. Having contraindications of iTBS (e.g., history of seizures, intracranial metallic implants, microprocessor implants in the body, suffering from tumorous, and pregnancy); 4. Cognitive impairment with the mini-mental state examination (MMSE) score < 27; 5. Treatment with benzodiazepines, baclofen, antiepileptics and antidepressants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Berg Balance Scale;Trunk Impairment Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Smart Equitest Balance Master System;surface electromyography recording;functional near-infrared spectroscopy;Fugl-Meyer assessment scale for lower extremity;Barthel Index; | — |
Countries
China
Contacts
Public ContactQiang Gao
West China Hospital, Sichuan University
Outcome results
None listed