Cognitive aging
Conditions
Interventions
Sponsors
State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University
Eligibility
Sex/Gender
All
Age
50 Years to 78 Years
Inclusion criteria
Inclusion criteria: Outpatients or inpatients aged 50-80 years and community elderly population, regardless of gender, education level >= 6 years.
Exclusion criteria
Exclusion criteria: 1. Patients with severe caridiac, liver, and kidney dysfunction; 2. Patients with other mental and neurological disorders and malignant tumors; 3. The Geriatric Depression Scale (GDS) score < 10 points, excluding cognitive impairment due to emotions; 4. Those who have participated or are participating in other drug trials within three months before being selected; 5. Poor compliance, severe illness or life-threatening expected survival time is less than 1 year, who cannot complete the course of treatment; 6. Use other cognitive-improving drugs such as ChEIs or other psychotropic drugs within the past three months; 7. MRI contraindications.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mini-MentStatus Examination, MMSE; | — |
Secondary
| Measure | Time frame |
|---|---|
| Rey-Osterrich Complex Figure Test;Stroop Color Word Test, SCWT;Trail Making Test;Clock Drawing Test;Symbol Digit Modalities Test;Verbal Fluency Test;Boston Naming Test;Auditory Verbal Learning Test, AVLT; | — |
Countries
China
Contacts
Public ContactZaizhu Han
Outcome results
None listed