esophageal squamous cell carcinoma
Conditions
Interventions
Group of PET/CT + chest CT enhanced examination:Nil
Sponsors
Renji Hospital, Shanghai Jiaotong University School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. The AJCC staging of the 8th edition suggests that patients of thoracic esophageal squamous cell carcinoma of cT1-2N+M0 or cT3-4aNanyM0; 2. Aged 18-75 years, regardless of gender; 3. Patients with thoracic esophageal squamous cell carcinoma confirmed by cell/tissue pathological biopsy have not previously received systemic anti-tumor therapy; 4. Patients with cT1-2N+M0 or cT3-4aNanyM0 evaluated by imaging examiation will accept the neoadjuvant therapy; 5. KPS is greater than 90 points; 6. Through the discussion by MDT, the general condition can meet the requirements of neoadjuvant therapy; 7. Reproductive age women must finish the pregnant text within 7 days before enroll in the study. Only those with negative result can be included in this trial. Reproductive age patients and their sexual partners should take reasonable contraceptive measures until at least 180 days after the end of the study; 8. Voluntarily enrolled in the trial and signed the consent form.
Exclusion criteria
Exclusion criteria: 1. Combined with the second primary tumor; 2. Cases with previous thoracic and abdominal surgery; 3. Previous history of radiotherapy and chemotherapy; 4. Previous history of esophageal endoscopic treatment; 5. People who are allergic to drugs used in clinical trials, allergic constitution or allergic to multiple drugs; 6. Female patients who plan to become pregnant within 6 months, or are in pregnancy or lactation; 7. Patients who can't or refuse surgical treatment after new adjuvant therapy; 8. Claustrophobic patients; 9. Those who can't stand lifting with both arms and lying down for 15-30 minutes; 10. Those who have participated in clinical trials or are participating in other clinical trials in the past 1 month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Parameters of PET/CT for tumor T staging and N staging; | — |
Countries
China
Contacts
Public ContactZhiyong Sun
Renji Hospital, Shanghai Jiaotong University School of Medicine
Outcome results
None listed