Allergic Rhinitis
Conditions
Interventions
CSGB group:Cervical sympathetic ganglion block
CTRL group:Oral drugs
Sponsors
Peking University First Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with allergic rhinitis in otolaryngology department and pain clinic of our hospital; 2. Aged 18-65 years; 3. Clinical diagnosed with moderate-to-severe allergic rhinitis (moderate to severe symptoms, influence the quality of life and sleep) according to the guideline of ARIA in 2016.
Exclusion criteria
Exclusion criteria: 1. Received stellate ganglion block or other nerve blocks within a month; 2. Combined with other nasal diseases leading to rhinitis, including non-allergic rhinitis, chronic sinusitis with/without polyps, and severe septal deviation requiring surgical intervention; 3. History of allergen specific immunotherapy in the past 5 years; 4. History of systemic hormone therapy in the past three months; 5. History of nasal and eye surgery within a month; 6. Pregnancy,lactating women, or prepare for pregnacy in six months; 7. ASA grade >= IV; 8. Incomplete medical records, incomplete follow-up data, or patients unable to cooperate, communicate, or follow up for various reasons, such as severe dementia, speech disorders, or end-stage disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Composite symptom and medication scores-nose 1 month after intervention; | — |
Secondary
| Measure | Time frame |
|---|---|
| Composite symptom and medication scores-nose 3 months aftter intervention;Composite symptom and medication scores-eye 1 month and 3 months after intervention;Visual Analogue Scale score 1 month and 3 months after intervention;Total nasal symptom score 1 month and 3 months after intervention;Treatment Emergent Symptom Scale 1 month and 3 months after intervention;MAS/sJIA score 1 month and 3 months after intervention;Rhinoconjunctivitis Quality of Life Questionnaire score 1 month and 3 months after intervention;Patient global impression of change 1 month and 3 months after intervention;Incidences of side effects for both CSGB and CTRL gruop, 1 month and 3 months after intervention, respectively; | — |
Countries
China
Contacts
Public ContactLin Zengmao
Peking University First Hospital
Outcome results
None listed