Mild to moderate acne vulgaris
Conditions
Interventions
Experimental group:2% supramolecular salicylic acid
The control group:Differin Adapalene gel
Sponsors
The Third Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: 1. Male or female aged 18-35 years; 2. Patients with mild to moderate (grade I-II according to the Pillsbury grading system & International improved classification) facial acne vulgaris; 3. 15 < number of acnes + papules + pustules on the subject face (the sum of one or three types of lesions) < 50; 4. Voluntary participation and signing informed consent.
Exclusion criteria
Exclusion criteria: 1. The face has other skin diseases that may affect the judgment of the results ( Except for melasma, freckles and seborrheic dermatitis); 2. People who are allergic to test drugs or have high sensitivity; 3. Pregnancy and lactation; 4. Liver function and/or kidney function laboratory test results are clinically abnormal judged by the doctor; 5. Patients with secondary acne, such as occupational acne and acne caused by corticosteroids; 6. Patients treated with oral antibiotics, glucocorticoids, anti-androgens such as spironolactone and other acne treatment drugs; or treated with physical therapy; or treated with salicylic acid and alpha hydroxy acid within 4 weeks before the trial; 7. Those who took oral tretinoin drugs within 2 months before the trial (6 months before acitretin drugs); 8. Patients with a history of facial injections or surgery 2 months before the trial; 9. Patients with immunodeficiency diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| acne;pimples;pustules; | — |
Secondary
| Measure | Time frame |
|---|---|
| Trans Epidermal Water Loss;Skin water content;Sebum;Pores;Fine lines; | — |
Countries
China
Contacts
Public ContactLai Wei
The Third Affiliated Hospital of Sun Yat-sen University
Outcome results
None listed