Severe tuberculosis
Conditions
Interventions
Case series:none
Sponsors
Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
No minimum to 100 Years
Inclusion criteria
Inclusion criteria: Age and gender are not limited; For patients with severe pulmonary tuberculosis, imaging and grading diagnosis meet any of the following criteria: 1. Damaged lung >= 1 lung lobe; 2. Chest CT showed lesions in >= 3 lobes; 3. Hematogenous disseminated pulmonary tuberculosis; 4. Caseous pneumonia; 5. Tuberculosis of bronchus; 6. Multiple hilar or mediastinal lymph nodes were enlarged in primary pulmonary tuberculosis; 7. Rifampicin-resistant, multidrug resistant, multidrug resistant, or pan-drug resistant tuberculosis; 8. Merge at least 2 holes larger than 8mm; 9. Tuberculous massive hemoptysis; 10. Pulmonary tuberculosis with acute infection (including multidrug-resistant bacterial infection, fungal infection or multiple infection); 11. Extrapulmonary tuberculosis (1) Intracranial tuberculosis, spinal cord and/or meningeal tuberculosis; (2) Pleural effusion and pericardial effusion: 1) Empyema or pyopneumothorax, hemopneumothorax, tracheobronchopleural fistula and severe infection; 2) Heart failure due to tamponade or constrictive pericarditis; (3) Multiple sites of lymphatic tuberculosis or surgical treatment is necessary: 1) Cervical lymphatic tuberculosis; 2) Mediastinal lymphatic tuberculosis; 3) Tuberculosis of abdominal or retroperitoneal lymph nodes; (4) Intraperitoneal tuberculosis, tuberculous peritonitis (peritoneal effusion or multiserous effusion): 1) Intestinal tuberculosis causes complete or incomplete intestinal root obstruction or perforation or massive bleeding or severe abdominal infection; 2) Digestive system tuberculosis leads to massive gastrointestinal bleeding, etc; (5) Tuberculosis of musculoskeletal system: 1) Tuberculosis of the spine (neck, chest, waist, sacral vertebrae); 2) Other bones; 3) Complicated with peripheral abscess; (6) Urinary or renal tuberculosis: 1) Renal tuberculosis causes renal failure or bleeding from injured vessels; 2) Ureteral stricture or obstruction due to urinary tuberculosis; (7) Adrenal tuberculosis with adrenocortical hypofunction; (8) The hepatic tuberculosis.
Exclusion criteria
Exclusion criteria: 1. Patients without definite diagnosis at discharge; 2. Patients judged by the investigator to be unsuitable for inclusion in this protocol; 3. Discharged with a diagnosis of central nervous system tuberculosis, or tuberculous meningitis, or tuberculous meningiitis, or tuberculous meningoencephalitis, or tuberculous encephalitis, or tuberculous brain abscess, or spinal tuberculosis, or tuberculous hydrocephalus, and is currently participating in other clinical studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 2-year survival and disability rates; | — |
Countries
China
Contacts
Public ContactQing Ning
Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology
Outcome results
None listed