High mechanical index ultrasound combined with sulfur hexafluoride microbubbles in the treatment of myocardial microcirculation disfunction in patients with acute myocardial infarction after PCI

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200065340

Enrollment

Unknown

Registered

2022-11-02

Start date

2020-06-01

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute myocardial infarction

Interventions

Treatment Group:High mechanical index ultrasound combined with sulfur hexafluoride microbubble flash and medicine treatment

control group:medicine treatment

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed with acute myocardial infarction were treated with PCI with TIMI blood flow level 0~2 within 12 hours of onset; 2. Aged 18-80 years; 3. Signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with previous diagnosis of myocardial infarction; 2. Patients with suspected or previous allergy to sulfur hexafluoride; 3. Pregnant women and lactating women; 4. It is expected that the follow-up cannot be completed; 5. Other clinical trials are under way; 6. Persons with intellectual or mental disabilities; 7. Survival less than 2 years; 8. Thrombolysis before PCI; 9. Hemodynamic instability.

Design outcomes

Primary

Measure	Time frame
Left ventricular end-diastolic volume;Left ventricular end-systolic volume;Left ventricular ejection fraction;	—

Countries

China

Contacts

Public ContactYin Hongning

The Second Hospital of Hebei Medical University

eveningyhn@163.com+86 15803213191

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026