quality of recovery in general anesthesia in elderly patients
Conditions
Interventions
Experimental group1:Remimazolam 0.5-1.0 mg/kg/h was maintained during the operation
Experimental group2:Remimazolam combined with 0.5 MAC sevoflurane was maintained during the operation
Sponsors
Dongguan People's Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Subjects have a full understanding of the purpose and significance of this trial, volunteer to participate in this clinical trial, and sign an informed consent; 2. Patients who need general anesthesia for tracheal intubation for elective abdominal surgery; 3. Aged 60-80 years, gender is not limited; 4. ASA I-III.
Exclusion criteria
Exclusion criteria: 1. Those who are allergic to benzodiazepines, propofol, opioid and other pharmaceutical ingredients or components that may be used in the research; 2. Those who use of benzodiazepines or opioids within 1 month; 3. Those who have a history of mental illness; 4. Those who have cognitive dysfunction; 5. BMI >= 28 kg/m2; 6. Foreseeable difficult intubation; 7. Bradycardia, heart rate < 55 beats/min; 8. Patients with severe heart, lung, liver, and kidney function abnormalities; 9. Those with a history of allergic diseases, with previous malignant hyperthermia and previous history of epilepsy; 10. Those with fat metabolism disorders; 11. Those with myasthenia gravis; 12. Patients unable to understand written information or informed consent regarding the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QoR-15 score on the first postoperative day; | — |
Secondary
| Measure | Time frame |
|---|---|
| QoR-15 score on postoperative day 3;Blood flow dynamics;Anesthesia recovery time; | — |
Countries
China
Contacts
Public ContactXie Haihui
Dongguan People's Hospital
Outcome results
None listed