Efficacy evaluation of early respiratory rehabilitation combined with Internet-based patient management model in patients with chronic obstructive pulmonary disease: a pragmatic, multicenter, randomized controlled trial

Clinical research and achievement transformation of key diagnosis and treatment technologies for major respiratory diseases

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200065327

Enrollment

Unknown

Registered

2022-11-02

Start date

2023-03-31

Completion date

Unknown

Last updated

2024-04-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

AECOPD

Interventions

A:AECOPD early respiratory rehabilitation therapy + Internet based patient management

B:AECOPD early respiratory rehabilitation treatment + routine follow-up management

C:Traditional rehabilitation + routine follow-up

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged 40-75 years; 2. Patients with moderate to severe COPD admitted for treatment due to acute exacerbation, GOLD 2-4, the diagnosis meets the diagnostic criteria of the GOLD COPD Global Initiative in 2022; 3. Within 1 week after admission; 4. The residents of the research center are not planned to move out during the study period; 5. Volunteer to participate in the study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Pregnant or lactating women; 2. Subjects who are participating in clinical trials or intervention studies of other drugs; 3. History of active pulmonary tuberculosis, and after partial, lobectomy or pneumonectomy; 4. Those with an expected survival period less than 6 months, such as uncontrolled advanced malignant tumors, have a history of acute myocardial infarction, unstable angina, acute stroke, and acute heart failure within 6 months; 5. Patients with liver failure or renal failure requiring dialysis treatment; 6. The researcher judged that other conditions were not suitable for the study.

Design outcomes

Primary

Measure	Time frame
90 day acute exacerbation readmission rate;12 month readmission rate due to acute exacerbation;	—

Secondary

Measure	Time frame
All cause mortality at 3, 6 and 12 months;Times of acute exacerbation at 3, 6 and 12 months;Proportion of people with acute exacerbations >= 2 times within 12 months;Time of first acute exacerbation;Self assessment test (CAT score), dyspnea score (mMRC score) and quality of life evaluation (SGRQ score) for patients with chronic obstructive pulmonary disease at 3, 6 and 12 months;Completion rate of respiratory rehabilitation therapy at 3, 6 and 12 months;Completion rate of respiratory rehabilitation therapy at 3, 6 and 12 months;Patient treatment compliance at 3, 6 and 12 months;12 month patient and doctor satisfaction scores;Incidence rate of adverse events;6 minutes walk distance;Completion rate of respiratory rehabilitation therapy at 3, 6 and 12 months;	—

Measure

Time frame

All cause mortality at 3, 6 and 12 months;Times of acute exacerbation at 3, 6 and 12 months;Proportion of people with acute exacerbations >= 2 times within 12 months;Time of first acute exacerbation;Self assessment test (CAT score), dyspnea score (mMRC score) and quality of life evaluation (SGRQ score) for patients with chronic obstructive pulmonary disease at 3, 6 and 12 months;Completion rate of respiratory rehabilitation therapy at 3, 6 and 12 months;Completion rate of respiratory rehabilitation therapy at 3, 6 and 12 months;Patient treatment compliance at 3, 6 and 12 months;12 month patient and doctor satisfaction scores;Incidence rate of adverse events;6 minutes walk distance;Completion rate of respiratory rehabilitation therapy at 3, 6 and 12 months;

—

Countries

China

Contacts

Public ContactZhao Hongmei

China Japan Friendship Hospital

lucy0500@163.com+86 13701135896

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026