unexplained recurrent abortion
Conditions
Interventions
Control:Dydrogesterone + placebo
Intervention group:Dydrogesterone + Zishen Yufei wan
Sponsors
Chongqing Maternal and Child Health Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 42 Years
Inclusion criteria
Inclusion criteria: 1. Aged 20-40 years; 2. Spontaneous abortion >= 2 consecutive times with the same partner; 3. Patients and their family members fully understood the content of the study and voluntarily signed informed consent; 4. Gestational age < 8 weeks.
Exclusion criteria
Exclusion criteria: 1. Chromosomal abnormalities in embryos of either spouse; 2. Thrombolysis; 3. Uncured uterine anatomical abnormalities, including uterine congenital malformations, cervical insufficiency, intrauterine adhesions, uterine fibroids, etc.; 4. Fetal abnormality; 5. Allergic to or was prohibited by known drug ingredients; 6. Bleeding caused by vaginal and cervical factors; 7. Suffering from serious organic lesions of the heart, liver, kidney or brain, and serious physical diseases or malignant tumors; 8. BMI >= 30 kg/m2; 9. With autoimmune diseases that have been identified to be associated with recurrent abortion; 10. Had used hormone drugs one month before randomization, and had taken other kidney tonifying Chinese patent medicine or traditional Chinese medicine decoction one month before randomization; 11. Endocrine diseases, such as hyperlactatemia, thyroid diseases, diabetes mellitus, polycystic ovary syndrome, etc.; 12. The investigator did not consider it appropriate to participate in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| live birth rate; | — |
Countries
China
Contacts
Public ContactHao Lijuan
Chongqing Maternal and Child Health Hospital
Outcome results
None listed