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Application of opioid-free multi modal anesthesia strategy in laparoscopic cholecystectomy

Effect of opioid-free anesthesia on postoperative recovery quality of patients undergoing laparoscopic cholecystectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200065324
Enrollment
Unknown
Registered
2022-11-02
Start date
2022-11-05
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute cholecystitis

Interventions

Opioid free group:Propofol combined with esketamine and dexmedetomidine for general anesthesia
Opioid group:Propofol combined with sufentanil and remifentanil

Sponsors

The First People's Hospital of Lianyungang
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 20-60 years; 2. American Society of Anesthesiologists Class I or II.

Exclusion criteria

Exclusion criteria: 1. Patients with severe heart or lung disease or psychiatric problems (chronic depression or severe bipolar disorder) before surgery; 2. Patients who continue to take steroids; 3. Chronic opioid users or opioid abusers; 4. Allergic to any drug in the test; 5. Body mass index > 35 kg/m2; 6. Pregnant, lactating or menstruating women; 7. Liver, kidney or heart insufficiency, diabetes, chronic pain history.

Design outcomes

Primary

MeasureTime frame
15-item postoperative recovery quality rating scale;—

Secondary

MeasureTime frame
Numeric Rating Scale;Occurrence of postoperative adverse reactions;—

Countries

China

Contacts

Public ContactLuan Hengfei

The First People's Hospital of Lianyungang

haoconghui2022@163.com+86 18961325313

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026