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Intracellular FGF1 promotes invasion and migration in thyroid carcinoma via HMGA1 independent of FGF receptors

Intracellular FGF1 promotes invasion and migration in thyroid carcinoma via HMGA1 independent of FGF receptors

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200065323
Enrollment
Unknown
Registered
2022-11-02
Start date
2022-11-05
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid cancer

Interventions

Thyroid cancer group:collecting tissues of thyroid cancer
Thyroid normal group:collecting thyroid Para-cancerous tissues

Sponsors

The First Affiliated Hospital of University of South China
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients who had undergone thyroid surgery for the first time and had undergone lymph node dissection in Central District or neck dissection at the same time; 2. The diagnosis of thyroid thyroid cancer was confirmed by intraoperative frozen section and postoperative pathology; 3. No history of chemotherapy, radiotherapy and immunotherapy was found before operation; 4. Aged 18-80 years.

Exclusion criteria

Exclusion criteria: 1. Recurrent thyroid cancer; 2. Complicated with other malignant tumor; 3. Pregnant and breast-feeding women.

Design outcomes

Primary

MeasureTime frame
Fibroblast growth factor 1;—

Secondary

MeasureTime frame
High mobility group protein A1;—

Countries

China

Contacts

Public ContactZuyao Chen

The First Affiliated Hospital of University of South China

chenzuyao@usc.edu.cn+86 15116840899

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026