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Effect of radiofrequency parathyroid ablation versus local injection of Paricalcitol in the treatment of secondary hyperparathyroidism in chronic kidney disease: a multicenter, randomized, controlled trial

Effect of radiofrequency parathyroid ablation versus local injection of Paricalcitol in the treatment of hyperparathyroidism secondary in chronic kidney disease: a multicenter, randomized, controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200065308
Enrollment
Unknown
Registered
2022-11-01
Start date
2022-11-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

secondary hyperparathyroidism

Interventions

Group A:local injection of Paricalcitol

Sponsors

The Second Affiliated Hospital, Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. iPTH >= 500 ng/L before dialysis; 2. Chronic kidney disease was diagnosed clearly and hemodialysis was maintained for more than 3 months; 3. Hyperparathyroidism has a causal relationship with uremia or chronic kidney disease; 4. Life expectancy assessed by a doctor is more than one year; 5. Aged 18-80 years.

Exclusion criteria

Exclusion criteria: 1. Kidney transplant patients; 2. Primary hyperparathyroidism and secondary hyperparathyroidism caused by non renal insufficiency; 3. The researchers judged that life expectancy was less than 12 months; 4. There was a history of acute coronary syndrome, severe arrhythmia, and myocardial infarction in the past 6 months; 5. Pregnancy.

Design outcomes

Primary

MeasureTime frame
Parathyroid Hormone;

Secondary

MeasureTime frame
calcium;phosphorus;alkaline phosphatase;

Countries

China

Contacts

Public ContactZhong Ling

The Second Affiliated Hospital, Chongqing Medical University

zhongling@hospital.cqmu.edu.cn+86 13896155895

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026