stroke
Conditions
Interventions
experiment group:On the basis of conventional treatment, the treatment of MNS-BCI synchronous NMES was performed
control group:On the basis of conventional treatment, the NMES was performed
Sponsors
Beijing Boai Hospital, China Rehabilitation Research Center, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Stroke patient Diagnostic criteria: 1. Stroke patients, including cerebral infarction and cerebral hemorrhage, met the diagnostic criteria for stroke formulated by the fourth National Conference on Cerebrovascular diseases in 1995; 2. Stroke was confirmed by CT or MRI; Unilateral inclusion criteria: 1. Of the limb hemiplegia patients with shoulder joint and elbow roughly normal limited (15?) or less passive ROM and wrist joints can remain in the neutral position; 2. Moderate to severe upper limb motor dysfunction, Brunnstrom stage = 27, able to execute treatment instructions, without severe cognitive and speech disorders, able to understand commands and communicate with therapists; 8. No visual impairment, international standard visual acuity chart examination of binocular visual acuity or corrected visual acuity >= 1.0; 9. The vital signs are stable, the disease does not progress, and the patient can tolerate 30 minutes of treatment daily. Healthy subjects Inclusion criteria: 1. Adult, aged > 18 years; 2. Right-handed hand dedness dedness Inventory (EHI); 3. Can take out about 40 minutes to participate in the test; 4. Junior high school education or above; 5. No visual impairment, the visual acuity of both eyes or corrected visual acuity >= 1.0 on the international standard visual acuity chart; 6. Normal muscle strength, ROM, no finger deformity, etc.; 7. No history of drug and alcohol dependence, no serious liver and kidney function diseases or other diseases that may affect brain structure and function, no other mental disorders; 8. Agreed to participate in the study and signed the informed consent form.
Exclusion criteria
Exclusion criteria: Stroke patient 1. Subarachnoid hemorrhage, venous sinus thrombosis, transient ischemic attack, progressive stroke or reversible cerebral ischemia; 2. Lesions located in bilateral cerebral hemispheres, cerebellum or brainstem; 3. There are contraindications of NMES treatment: skin injury or skin disease (such as eczema, etc.), acute infection (such as osteomyelitis, etc.), vascular diseases (such as thrombosis or phlebitis), metal implants and cardiac pacemaker, skin injury or infection at the contact site of upper limb and electrode piece or allergy to electrode piece, etc. 4. Combined with other major diseases, such as heart, lung, liver, kidney and other organ diseases or failure; 5. Patients with hand fractures, skin ulcers, open wounds or deformities are not suitable for hand joint range of motion training or cannot wear hand training equipment; 6. Receive invasive treatment such as surgery; 7. There are other clinical problems affecting the assessment results, such as poor vision, recent or unhealed fractures, vestibular diseases, skull defects, visual field defects, lateral neglect, visual impairment, severe aphasia or hearing impairment, communication difficulties, etc. 8. The presence of other neurological diseases, such as multiple sclerosis and Parkinson's disease, or severe psychological problems, such as post-stroke depression (Hamilton Depression Scale < 7). Healthy subjects An event affecting the experimental results occurred while waiting for the test to complete the test.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| fNIRS; | — |
Secondary
| Measure | Time frame |
|---|---|
| sEMG;Rehabilitation Scale evaluation; | — |
Countries
China
Contacts
Public ContactCui Yao
Beijing Boai Hospital, China Rehabilitation Research Center, Capital Medical University
Outcome results
None listed