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Effect of Progestin-primed Ovary Stimulation on IVF outcomes in women with PCOS: A multicenter randomized controlled clinical trial

Effect of Progestin-primed Ovary Stimulation on IVF outcomes in women with PCOS: A multicenter randomized controlled clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200065297
Enrollment
Unknown
Registered
2022-11-01
Start date
2022-11-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Interventions

PPOS Group:PPOS regimen
GnRH-ant Group:GnRH antagonist regimen

Sponsors

Shanghai East Hospital,Tongji University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1) The diagnosis criteria of PCOS is based on the 2003 Rotterdam criteria, that is, two of the following three criteria can be met: 1. hyperandrogenism or clinical hyperxiong signs; 2. Rare ovulation or anovulation; 3. More than 12 follicles in one ovary were detected by ultrasound; 2) Women patients<40 years old; 3) Indicated for IVF-ET treatment; 4) Patients undergoing IVF-ET for the first time

Exclusion criteria

Exclusion criteria: 1) Patients with systemic diseases unsuitable for pregnancy; 2) Patients with endometriosis; 3) Patients with acute genital tract inflammation and genital tract tumors; 4) Patients with uterine deformities; 5) Patients with a history of recurrent abortion; 6) Patients receiving hormone replacement therapy in the last 3 months.

Design outcomes

Primary

MeasureTime frame
Cumulative live birth rate;

Secondary

MeasureTime frame
Number of oocytes retrievedl;Number of mature oocytes;Number of normal fertilization;Incidence rate of premature LH surge;Clinical pregnancy rate;Abortion rate;

Countries

China

Contacts

Public ContactSun Lihua

Shanghai East Hospital, Tongji University School of Medicine

lihua-sun@163.com+86 021 20334527

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026