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The Clinical efficacy and safety of image-guided hypofractionation Intensity-modulated radiotherapy in locally advanced non-small cell lung cancer

The Clinical efficacy and safety of image-guided hypofractionation Intensity-modulated radiotherapy in locally advanced non-small cell lung cancer

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200065290
Enrollment
Unknown
Registered
2022-11-01
Start date
2022-01-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non small cell lung cancer

Interventions

one:Hyperfraction radiotherapy

Sponsors

Beijing Luhe Hospital Affiliated to Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 90 Years

Inclusion criteria

Inclusion criteria: (1) Voluntary participation and written informed consent (2) Gender is not limited, age from 18 to 75 (3) Histologically or cytologically proven NSCLC (4) Stage III or oligometastatic stage IV NSCLC (5) All patients could not tolerate or refuse the operation (6) The size of the primary lesion was limited to = 70, estimated survival > 3 months

Exclusion criteria

Exclusion criteria: (1) Patients who had received radiotherapy before enrollment (including patients who relapsed after radiotherapy); (2) Have serious comorbidities, such as hypertension, coronary heart disease, mental history or serious allergy history; (3) Refuse or fail to sign the informed consent for participating in the trial; (4) Estimated survival period <= 6 months.

Design outcomes

Primary

MeasureTime frame
DCR/ORR;Acute response to radiotherapy and chemotherapy;

Secondary

MeasureTime frame
Local recurrence rate / disease-free survival rate / overall survival rate;Late radiotherapy response;

Countries

China

Contacts

Public ContactGao Yuyan

82 Xinhua Road South, Tongzhou District, Beijing

liuqiteng1991@163.com+86 13718089976

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026