gynecological laparoscopic surgery
Conditions
Interventions
penehyclidine group:Penehycliane was used in anesthesia induction and postoperative intravenous analgesic pump
The placebo group:The same dose of normal saline was administered during anesthesia induction and postoperative intravenous analgesia pump
Sponsors
The First Affiliated Hospital of University of Science and Technology of China
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.ASA ?-?; 2. Age >=18 years; 3. BMI ? 35 kg/m^2; 4. Gynecological laparoscopic surgery.
Exclusion criteria
Exclusion criteria: 1.Preoperative use of anticholinergic drugs; 2.Patients could not understand the scoring items of various scales; 3. History of neurological and psychiatric diseases; 4. Severe heart, lung, liver and renal dysfunction; 5.Glaucoma and myasthenia gravis; 6. Previous pulmonary surgery history; 7.Preoperative chemoradiotherapy; Participated in other drug trials within 3 months.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Severity of postoperative nausea, vomiting rate, type and dose of rescue antiemetics,Comfort (Kolcaba's Comfort Scale) and quality of recovery (QoR-15) at 24h and 48h after operation; | — |
Primary
| Measure | Time frame |
|---|---|
| The incidence of PONV; | — |
Countries
China
Contacts
Public ContactWang Sheng
The First Affiliated Hospital of University of Science and Technology of China
Outcome results
None listed